In general, they are safe, Paskhover says. However, there can be complications when they are used, especially if someone is not trained to do so. Most problems aren't life-threatening, but in some cases, fillers have been linked to strokes and blindness. According to research published in Aesthetics, long-acting dermal fillers have higher rates of complications, such as infections and nodules.
The main drawback of purified hyaluronic acid dermal filler is the short half-life of hyaluronic acid in the dermis, estimated at 24 to 48 hours. Injectable dermal fillers can fill thin lips, improve shallow contours, smooth facial folds, eliminate wrinkles, and improve the appearance of scars. To date, no universally applicable dermal fillers have been developed, although manufacturers of hyaluronic acid-based products claim that their products are close to meeting many of the requirements of an ideal tissue augmentation agent. Dermal fillers can be composed of a variety of substances, some of natural origin and others synthetic.
Although hyaluronic acid-based dermal fillers have a low overall incidence of long-term side effects, occasional adverse outcomes have been documented, ranging from chronic lymphoplasmacytic inflammatory reactions to classic foreign body-type granulomatous reactions. This is partly because advances in medical science have spurred a number of new products, such as dermal fillers. The overall incidence of long-term adverse reactions secondary to dermal injection of hyaluronic acid dermal fillers is believed to be low, with the vast majority representing a chronic inflammatory reaction related to foreign bodies. Because dermal filler injections can cause significant complications, it's important to be under the care of a board-certified plastic surgeon who understands the risks and is trained and prepared to deal with any complications that may occur.
These injectables are also called dermal fillers, injectable implants, wrinkle fillers, and soft tissue fillers. Other available dermal fillers include those made of calcium hydroxyapatite, poly-L-lactic acid, polymethyl methacrylate, and autologous fat (fat that is transplanted from another part of the body). Dermal fillers approved by the U.S. Food and Drug Administration include Restylane, Juvederm Vollure, Juvederm Volbella, Juvederm Voluma, Radiesse, Sculptra and Belotero.
Individuals should discuss the provider's experience and training in dermal fillers and Botox before making a decision. You'll need to decide if the benefits will achieve your goals and if the risks and potential complications of dermal fillers are acceptable. So where does this leave the savvy consumer interested in non-invasive treatments to reduce signs of aging? Finding the right doctor to perform the dermal filling procedure is key. In addition to the correction of moderate to severe wrinkles and skin folds, hyaluronic acid-based dermal fillers are also widely used for scar correction and lip augmentation.
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